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“A leper in a leper colony would more often than not suffer from depression due to sudden abandon of known circle of family and friends, and the new unfamiliar surroundings. In addition, a leper, as opposed to any other sick person in the Middle Ages, could not expect visits, for leprosy was thought to be extremely contagious.”

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Souces: http://www.maggietron.com/med/epidemics.php

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